Cannabinoids may prevent infection with SARS-CoV-2, including variants

A new study published in the Journal of Natural Products of the American Chemical Society and American Society of Pharmacognosy has shown that isolated cannabinoids or those in hemp extracts have the potential to prevent and treat the infection with the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) – primarily by blocking viral cell entry.

One of the primary worries in the ongoing coronavirus disease 2019 (COVID-19) pandemic is the spread of many different viral variants known for successfully evading antibodies against early SARS-CoV-2 lineage. An additional concern is that currently implemented vaccination strategies rely on the receptor-binding domain (RBD) of spike glycoprotein from an initially identified SARS-CoV-2 strain.

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